Subject: Smallpox
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This is the first annual report of the New York Dispensary, covering the period from its opening on December 28, 1829, to January 1831. The report details the dispensary's activities, including its work on smallpox vaccination. It lists Daniel L. M. Peixotto among the attending physicians and notes Harmon Hendricks and M. M. Noah as donors.

A 1 1/2-page letter written by G. Sylvester in London, England to Tobias I. Tobias in New York City, New York on April 9, 1822. The letter contains family news, including details about a brother's experiences at a synagogue, the recovery of Elizabeth from smallpox, some business news, and Sylvester's desire to visit America.

Receipt issued to the Baltimore Hebrew Congregation in Baltimore, Maryland on July 24, 1833. The receipt mentions Jacob Leeser, the younger brother of Isaac Leeser. Jacob Leeser died of smallpox in 1834.